Die Sentrum is centred around a group of eight diverse councilors who work together in a helpline call centre and seek to help callers with their personal issues however each one of the councilors has their own challenges to overcome. The series explores compelling social realism scenarios against the present times in South Africa. The callers’' stories provide another layer of social reality in each episode. The office, politics, foibles, friendships, fights and frissons create texture and humour in the story strands. Alcoholism, domestic violence, a desperate search for love, and secret lifestyles are some of the subjects the counsellors need to deal with – not only over the telephone, but in their personal lives as well.